Clinical Informatics

Measuring Patient Data Density in EHRs to Understand Bias

The EHR Density Index (EDI), a covariate that quantifies how far a patient's documentation deviates from that of clinically similar patients, developed and validated on approximately 25,000 UNC Health patients as an adjustment for documentation-density bias in electronic health record (EHR) studies.

Active Jan 2024 – NC TraCS Institute Graduate Research Assistant

methods

statistical learning

funder

NC TraCS Institute

my role

Graduate Research Assistant

principal investigator

Emily Pfaff

Patients vary widely in how much data their electronic health records contain: sicker patients accumulate more. Comorbidity indices like Charlson and Elixhauser measure mortality risk, not documentation density. This project, with Emily Pfaff at the NC TraCS Institute, develops a covariate that lets analyses adjust for that uneven documentation.

A first manuscript is under review at the Journal of the American Medical Informatics Association. It introduces the EHR Density Index (EDI), which pairs utilization clusters from a Gaussian mixture model with within-cluster residuals across four OMOP domains (conditions, drugs, measurements, and procedures) to characterize how a patient’s documentation deviates from others with similar care patterns. The index was developed and validated on ~25,000 UNC Health patients.